|Home||» Products||» Formulations||» Drugs for Topical Applications|
Drugs for Topical Applications
Strobact Plus Cream
Strobact Plus Cream (Ofloxacin, Ornidazole, Terbinafine & Clobetasol) is an ideal combination of topical multi-specialty broad spectrum Antibacterial, Antifungal, Antiprotozoal, Corticosteroid and Anti-inflammatory agents highly effective in the treatment of primary and secondary infections of the skin such as Dermatophytosis, Psoriasis, Eczema, Trichomoniasis, etc. It is also called as a medicated multiple combination cream containing the generic medicines such as Ofloxacin, Ornidazole, Terbinafine Hydrochloride and Clobetasol Propionate.
Ofloxacin is a Broad-spectrum Antibacterial which belongsgroup of antibiotics. It is active against both gram-positive and gram-negative bacteria. Ofloxacin is used in the treatment of bacterial infections in the respiratory tract, kidney, skin, soft tissue, UTI, urethral and cervical gonorrhoea.
Mode of action: Ofloxacin acts by inhibiting the DNA gyrase enzyme (topoisomerase IV) which is necessary for the supercoiling of DNA during replication and thus inhibits bacterial cell division.
Ornidazole is an Antiamoebic agent which belongs to Nitroimidazole group of antibiotics used in amoeba and trichomonas infections. It is used for the treatment of severe intestinal and hepatic amoebiasis, giardiasis, and trichomoniasis of urogenital tract and bacterial vaginosis.
Mode of action: Ornidazole acts in the body by killing the bacteria that infect the inflamed skin.
Terbinafine is a synthetic broad-spectrum Antifungal agent belonging to the allylamine derivative. It is used to treat various fungal skin infections such as ringworm athleteâ€™s foot, etc. The antifungal activity of terbinafine is due to the selective inhibition of fungal squalene epoxidase, which increases squalene to toxic levels, and kills the fungal cell.
Mode of action: Terbinafine acts by preventing the growth of fungus by inhibiting most fungi which is pathogenic to man leading to deficiency in ergosterol and thus resulting in cell death.
Clobetasol is a synthetic active topical Corticosteroid belonging to the prednisolone derivative which is used in the treatment of various skin disorders including eczema, psoriasis, rashes, herpes labialis, alopecia areata, insect bites, and allergies. Clobetasol exhibits Anti-inflammatory, Antipruritic, and Vasoconstrictive properties.
Mode of action: It acts by decreasing certain immune responses, which reduces redness and itching of the skin.
Directions for use: Apply a small quantity 2-3 times daily on the affected area.
vMixed and complicated Fungal, Protozoal & Bacterial infections
v Mild to moderate Vaginitis
v Candidiasis and Trichomonas Infection
v Pruritis Vulvae
v Inflammatory Dermatoses
v Genito-urinary infections