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Home » Products » Bulk Drugs (APIs) » Ibuprofen

Ibuprofen

Ibuprofen
Ibuprofen
Product Code : 258
Product Description

Ibuprofen 

Synonym:  2-[4-(2-methylpropyl)phenyl]propanoic acid

CAS Number:  15687-27-1

Specifications

Purity: ≥99%

Physical Appearance: white

Storage :Store at room temperature. Solutions are stable for up to 3 months at -20°C

Properties

Molecular Weight:   206.3

Molecular Formula:   C13H18O2

Form:   Solid

Solubility:   Soluble in ethanol (25 mg/ml), chloroform (1:1), ether (1:2), acetone (1:1.5), aqueous solutions of alkali hydroxides and carbonates, dichloromethane, methanol (50 mg/ml), and ethyl acetate. Insoluble in water.

Melting Point:   75-77 °C

Boling Point:  157 °C at 4 mmHg

Flash Point:   216.7 °C

Vapor Pressure:   0.000139 mmHg at 25°C

Density:  1.03 g/cm3

Refractive Index:  n20D 1.52

Description : Ibuprofen inhibits Cox (cyclooxygenase) selectively, targeting Cox-1 and Cox-2. Ibuprofen has also been shown to inhibit PGH synthase-1 and PGH synthase-2 with similar potency. Ibuprofen is clinically useful as a nonsteroidal anti-inflammatory drug. Ibuprofen is reported to inhibit the netrophil-dependent edema response of rabbit skin to C5a/PGE23.




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